Chromatography Consumables, Analytical Services and Chromatography / Mass Spectrometry Training from Crawford Scientific
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Typical Applications
 
The Identification of Metabolites, Impurities and Degradation products can be assisted by the use of Accurate Mass MS techniques.  In this example a manufacturing impurity is analysed using Magnetic Sector Mass Spectrometry to obtain an Empirical Formula and Accurate Mass.
 
 
Using the mass spectrum of the parent active compound in conjunction with the empirical formula and the impurity spectrum, the structure of the impurity was characterised and the manufacturing problem successfully identified.
 
 


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